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Another huge problem for Pfizer
Having one of the most epic pharmaceutical failures, Pfizer is going take a charge of 2.8 billion dollars because of weak sales of diabetic drug.
Ranbaxy Laboratories got an import ban to US...
In September this year, the US Food and Drug Administration (FDA) issued an import alert to a third of Ranbaxy Laboratories manufacturing facility in India, because of a quality concernment.
Because of the latest FDA actions, the final dedicated to US market Ranbaxy plant in India was banned to import their products to US. Also the similar import bans are still having the other 2 plants of Ranbaxy in India from 2008 year.

Sildenafil

What is Sildenafil citrate?

Nowadays mostly every person in the world has heard about such treatment as Viagra (Sildenafil citrate). It is used to be known as one of the most effective drug for the treatment of erectile dysfunction and the world drug for sexual desire. The invention of the treatment made on the basis of sildenafil citrate has carried out a revolution for many men suffering from disorders of potency. Sildenafil citrate is preferred by most men because of the reliable effect when using the drug. Sildenafil enables both completely cure impotence and improvement of sexual intercourse in healthy men. Taking Sildenafil is able to return you to normal sexual life if you are having problems getting an erection, impotence in the result of organic problems, psychological or of mixed descent.

sildenafil

Sildenafil citrate is effective only if a man feels excitement and natural sexual arousal. That is, the drug allows you to control your erection at will. It works on the natural functions of the body, strengthening the erection, making it longer and more stable.

How does it work?

Sildenafil effect increases blood flow to the pelvis, allowing blood to flow to the cavernous bodies of the penis, thereby contributing to an erection. As a result, there is an erection that persists for 4-5 hours after ingestion.

Dose and of usage of sildenafil citrate

The drug is taken orally 30-60 minutes before the sexual intercourse. For adults the optimal single dose is 50 mg just once a day. Depending on the necessity, efficacy and tolerability of the drug, the dose may be reduced to 25 mg or increased to 100 mg. The maximum single dose is 100 mg per day. It is not recommended to take Sildenafil with alcohol. But it may be taken with or without water or food.

It is not recommended for people with hypersensitivity to sildenafil, as well as those who suffer from the following diseases: leukemia, multiple myeloma, sickle cell anemia, severe diseases, priapism and penile deformation of the cardiovascular system.

Are there any side effects from Sildenafil citrate?

Sildenafil is generally well tolerated, but there are some side effects which are rare and mild: headache, dizziness, flushing, nasal congestion, disturbance of color perception, blurred vision.

Contraindications:

    The drug is contraindicated for individuals with:
  • hypersensitivity to the drug and with anatomical deformation of the penis (Peyronie's disease, angulation, cavernous fibrosis)
  • increased tendency to bleed
  • exacerbation of peptic ulcer disease of the gastrointestinal tract
  • disruption of the liver, especially severe renal failure or cirrhosis
  • diseases that develop priapism, including leukemia, multiple myeloma, and sickle cell anemia
  • hypertension or severe hypotension
  • various heart disease, including unstable angina, arrhythmias, and in the form of dangerous cardiac insufficiency

If the patient has suffered from myocardial infarction or a stroke, in the next six months, the drug should not be used. It is strictly forbidden simultaneous use of the drug with nitric oxide donators and nitrates or to those men who are contraindicated sexual activity.

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